PD-1/PD-L1-IN-36
PD-1/PD-L1-IN-36 (Compound 2k) is a PD-1/PD-L1 complex inhibitor (IC50: 15 nM) . PD-1/PD-L1-IN-36 can be used for research of cancer immunotherapy[1].
Product Specifications
CAS Number
[2714327-65-6]
UNSPSC
12352005
Target
PD-1/PD-L1
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/pd-1-pd-l1-in-36.html
Purity
98.0
Solubility
10 mM in DMSO
Smiles
O=C([C@H]1N(CC2=CC=C(OCC3=C(Br)C(C4=CC=CC=C4)=CC=C3)C(Br)=C2)CCCC1)O
Molecular Formula
C26H25Br2NO3
Molecular Weight
559.29
References & Citations
[1]Konieczny M, et al. Di-bromo-Based Small-Molecule Inhibitors of the PD-1/PD-L1 Immune Checkpoint. J Med Chem. 2020 Oct 8;63 (19) :11271-11285.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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