EN884
Product Specifications
UNSPSC Description
EN884 is a BRD4 degrader via a SKP1- and proteasome-dependent manner. EN884 can be used in synthetic proteolysis targeting chimeras (PROTACs)[1].
Target Antigen
Epigenetic Reader Domain; Target Protein Ligand-Linker Conjugates
Type
Reference compound
Related Pathways
Epigenetics;PROTAC
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/en884.html
Solubility
10 mM in DMSO
Smiles
O=C(N1CCC(CC1)CC2=CC=CN=C2)C=C
Molecular Weight
230.31
References & Citations
[1]Seong Ho Hong, et al. Exploiting the Cullin E3 Ligase Adaptor Protein SKP1 for Targeted Protein Degradation. bioRxiv. 2023.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-163019/EN884-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-163019/
Clinical Information
No Development Reported
CAS Number
2189497-60-5
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