RNA polymerase-IN-2
RNA polymerase-IN-2 (compound 5) is s DNA-dependent RNA polymerase inhibitor. RNA polymerase-IN-2 inhibits CYP isozymes[1].
Product Specifications
CAS Number
2447106-79-6
UNSPSC
12352005
Target
DNA/RNA Synthesis
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/rna-polymerase-in-2.html
Solubility
10 mM in DMSO
Smiles
O[C@H]([C@H]([C@H]([C@H]([C@@H]([C@@H]([C@@H](OC)/C=C/O1)C)OC(C)=O)C)O)C)[C@@H](C)/C=C/C=C(C)\C(NC2=C3OC4=C(C(O)=CC(OCCN(C)C)=C4)N=C3C5=C6C([C@]1(C)OC6=C(C)C(O)=C5C2=O)=O)=O
Molecular Formula
C47H57N3O14
Molecular Weight
887.97
References & Citations
[1]Thomas Nittoli, et al. Potent Rifampicin derivatives can clear MRSA infections at single low doses when concomitantly dosed with Vancomycin. J Antibiot (Tokyo) . 2023.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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