MBL-IN-2
Product Specifications
UNSPSC Description
MBL-IN-2 ((2R, 2R')-5αC) is an inhibitor of Metallo-β-lactamase (MBL) that can inhibit New Delhi Metallo-β-lactamase-1 (NDM-1) with an IC50 of 0.3 μM. MBL-IN-2 ((2R, 2R')-5αC) can be used for the study of resistance to β-lactam antibiotics[1].
Target Antigen
Bacterial; Beta-lactamase
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/mbl-in-2.html
Solubility
10 mM in DMSO
Smiles
SC[C@@H](C(F)(F)F)C(N1CCC[C@@H]1C(O)=O)=O
Molecular Weight
271.26
References & Citations
[1]Kondratieva A, et al. Fluorinated captopril analogues inhibit metallo-β-lactamases and facilitate structure determination of NDM-1 binding pose[J]. European Journal of Medicinal Chemistry, 2024: 116140.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-162174/MBL-IN-2-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-162174/
Clinical Information
No Development Reported
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