WYZ90
WYZ90 ((compound 6a) is a potent and selective COX-2 inhibitor with IC50 values of 75, 5734, 19940 nM for COX-2, COX-1 and DPPH, respectively. WYZ90 shows antioxidant and analgesic activity[1].
Product Specifications
UNSPSC
12352005
Target
COX
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/wyz90.html
Solubility
10 mM in DMSO
Smiles
O=C1C(CC2=CC=C(C(NO)=O)C=C2)=C(C)NN1C3=CC=CC=C3
Molecular Formula
C18H17N3O3
Molecular Weight
323.35
References & Citations
[1]Wang Y, et al. Hybrids of selective COX-2 inhibitors and active derivatives of edaravone as COX-2 selective NSAIDs with free radical scavenging activity: Design, synthesis and biological activities. Eur J Med Chem. Published online January 18, 2024.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
COX-1; COX-2
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