Anti-inflammatory agent 72

Anti-inflammatory agent 72 (compound 5) is a novel resveratrol derivative hybrid with benzoylhydrazine. Anti-inflammatory agent 72 shows anti-inflammatory and antioxidant activities by activating Nrf2 and inhibiting NF-κB p65/iNOS and MAPKs signaling pathways[1].

Product Specifications

CAS Number

[9007-83-4]

UNSPSC

12352005

Target

Keap1-Nrf2; NF-κB; p38 MAPK

Type

Reference compound

Related Pathways

MAPK/ERK Pathway; NF-κB

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/anti-inflammatory-agent-72.html

Solubility

10 mM in DMSO

Smiles

OC1=CC=C(/C=C/C2=CC(O)=CC(O)=C2/C=N\NC(C3=CC=C(O)C=C3)=O)C=C1

Molecular Formula

C22H18N2O5

Molecular Weight

390.39

References & Citations

[1]Lu JX, et al. Design, synthesis and evaluation of antioxidant and anti-inflammatory activities of novel resveratrol derivatives as potential multifunctional drugs. Eur J Med Chem. 2024 Jan 13;266:116148.