Anti-inflammatory agent 72
Anti-inflammatory agent 72 (compound 5) is a novel resveratrol derivative hybrid with benzoylhydrazine. Anti-inflammatory agent 72 shows anti-inflammatory and antioxidant activities by activating Nrf2 and inhibiting NF-κB p65/iNOS and MAPKs signaling pathways[1].
Product Specifications
CAS Number
9007-83-4
UNSPSC
12352005
Target
Keap1-Nrf2; NF-κB; p38 MAPK
Type
Reference compound
Related Pathways
MAPK/ERK Pathway; NF-κB
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/anti-inflammatory-agent-72.html
Solubility
10 mM in DMSO
Smiles
OC1=CC=C(/C=C/C2=CC(O)=CC(O)=C2/C=N\NC(C3=CC=C(O)C=C3)=O)C=C1
Molecular Formula
C22H18N2O5
Molecular Weight
390.39
References & Citations
[1]Lu JX, et al. Design, synthesis and evaluation of antioxidant and anti-inflammatory activities of novel resveratrol derivatives as potential multifunctional drugs. Eur J Med Chem. 2024 Jan 13;266:116148.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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