α-Amylase/α-Glucosidase-IN-8

α-Amylase/α-Glucosidase-IN-8 (Compound 7p) is a potent dual inhibitor of α-amylase and α-glucosidase, with IC50s of 10.19 and 10.33 μM, respectively. α-Amylase/α-Glucosidase-IN-8 has good anti-oxidant activity (IC50 = 14.93 μM) . α-Amylase/α-Glucosidase-IN-8 can be used for the research of diabetes[1].

Product Specifications

UNSPSC

12352005

Target

Amylases; Glycosidase

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/α-amylase-α-glucosidase-in-8.html

Solubility

10 mM in DMSO

Smiles

O=C(N(CC1=CC=CC([N+]([O-])=O)=C1)C/2=O)SC2=C/C3=CC=C(O)C(OCC)=C3

Molecular Formula

C19H16N2O6S

Molecular Weight

400.41

References & Citations

[1]Singh G, et al. 3,5-Disubstituted-thiazolidine-2,4-dione hybrids as antidiabetic agents: Design, synthesis, in-vitro and In vivo evaluation. Eur J Med Chem. 2024 Jan 12;266:116139.