α-Amylase/α-Glucosidase-IN-8
Product Specifications
UNSPSC Description
α-Amylase/α-Glucosidase-IN-8 (Compound 7p) is a potent dual inhibitor of α-amylase and α-glucosidase, with IC50s of 10.19 and 10.33 μM, respectively. α-Amylase/α-Glucosidase-IN-8 has good anti-oxidant activity(IC50 = 14.93 μM). α-Amylase/α-Glucosidase-IN-8 can be used for the research of diabetes[1].
Target Antigen
Amylases; Glycosidase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/α-amylase-α-glucosidase-in-8.html
Solubility
10 mM in DMSO
Smiles
O=C(N(CC1=CC=CC([N+]([O-])=O)=C1)C/2=O)SC2=C/C3=CC=C(O)C(OCC)=C3
Molecular Weight
400.41
References & Citations
[1]Singh G, et al. 3,5-Disubstituted-thiazolidine-2,4-dione hybrids as antidiabetic agents: Design, synthesis, in-vitro and In vivo evaluation. Eur J Med Chem. 2024 Jan 12;266:116139.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-162169/α-Amylase-α-Glucosidase-IN-8-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-162169/
Clinical Information
No Development Reported
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