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Diarctigenin

Diarctigenin is a selective Leishmania major dihydrofolate reductase-thymidylate synthase (LmDHFR-TS) inhibitor. Diarctigenin can be used for the research of tropical disease[1].

Product Specifications

UNSPSC

12352005

Target

Parasite

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/diarctigenin.html

Solubility

10 mM in DMSO

Smiles

OC1=C(C2=CC(C[C@H]3[C@H](CC4=CC(OC)=C(OC)C=C4)COC3=O)=CC(OC)=C2O)C=C(C[C@@H]5[C@@H](CC6=CC(OC)=C(OC)C=C6)COC5=O)C=C1OC

Molecular Formula

C42H46O12

Molecular Weight

742.81

References & Citations

[1]Muñoz-Vega MC, et al. Machine-Learning- and Structure-Based Virtual Screening for Selecting Cinnamic Acid Derivatives as Leishmania major DHFR-TS Inhibitors. Molecules. 2023 Dec 28;29 (1) :179.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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