Urease-IN-12
Urease-IN-12 (compound 5e) is a competitive urease inhibitor (IC50: 0.35 μM) with the potential to inhibit gastritis and peptic ulcer caused by Helicobacter pylori[1].
Product Specifications
UNSPSC
12352005
Target
Bacterial
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/urease-in-12.html
Solubility
10 mM in DMSO
Smiles
N[C@@H](CSCC(NC1=CC=C(Cl)C=C1)=O)C(O)=O
Molecular Formula
C11H13ClN2O3S
Molecular Weight
288.75
References & Citations
[1]Montazer MN, et al. Design, synthesis, and biological studies of the new cysteine-N-arylacetamide derivatives as a potent urease inhibitor. Naunyn Schmiedebergs Arch Pharmacol. 2024 Jan;397 (1) :305-315.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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