Urease-IN-12

Urease-IN-12 (compound 5e) is a competitive urease inhibitor (IC50: 0.35 μM) with the potential to inhibit gastritis and peptic ulcer caused by Helicobacter pylori[1].

Product Specifications

UNSPSC

12352005

Target

Bacterial

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/urease-in-12.html

Solubility

10 mM in DMSO

Smiles

N[C@@H](CSCC(NC1=CC=C(Cl)C=C1)=O)C(O)=O

Molecular Formula

C11H13ClN2O3S

Molecular Weight

288.75

References & Citations

[1]Montazer MN, et al. Design, synthesis, and biological studies of the new cysteine-N-arylacetamide derivatives as a potent urease inhibitor. Naunyn Schmiedebergs Arch Pharmacol. 2024 Jan;397 (1) :305-315.