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BDM91288

BDM91288 is an orally active AcrB efflux pump inhibitor of pyridinium piperazine. BDM91288 can enhance the in vivo efficacy of levofloxacin in the treatment of Klebsiella pneumoniae pulmonary infection in mouse models[1].

Product Specifications

CAS Number

2892824-53-0

UNSPSC

12352005

Target

Bacterial

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/bdm91288.html

Solubility

10 mM in DMSO

Smiles

ClC(C=C(C=C(N1CCNCC1)C=C2)C2=N3)=C3N4CCNCC4

Molecular Formula

C17H22ClN5

Molecular Weight

331.84

References & Citations

[1]Vieira Da Cruz A, et al. Pyridylpiperazine efflux pump inhibitor boosts in vivo antibiotic efficacy against K. pneumoniae. EMBO Mol Med. 2024 Jan;16 (1) :93-111.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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