BDM91288
BDM91288 is an orally active AcrB efflux pump inhibitor of pyridinium piperazine. BDM91288 can enhance the in vivo efficacy of levofloxacin in the treatment of Klebsiella pneumoniae pulmonary infection in mouse models[1].
Product Specifications
CAS Number
2892824-53-0
UNSPSC
12352005
Target
Bacterial
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/bdm91288.html
Solubility
10 mM in DMSO
Smiles
ClC(C=C(C=C(N1CCNCC1)C=C2)C2=N3)=C3N4CCNCC4
Molecular Formula
C17H22ClN5
Molecular Weight
331.84
References & Citations
[1]Vieira Da Cruz A, et al. Pyridylpiperazine efflux pump inhibitor boosts in vivo antibiotic efficacy against K. pneumoniae. EMBO Mol Med. 2024 Jan;16 (1) :93-111.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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