Urease-IN-11
Urease-IN-11 (Compound 6e) is a competitive urease inhibitor (IC50) =10.41 µM) . Urease-IN-11 can be used to study diseases such as urease-related gastritis and peptic ulcer[1].
Product Specifications
CAS Number
517906-12-6
UNSPSC
12352005
Target
Bacterial
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/urease-in-11.html
Solubility
10 mM in DMSO
Smiles
C1(C2=NN=C3N2N=C(C4=CC=C(C5=CC=CC=C5)C=C4)CS3)=CC=CN=C1
Molecular Formula
C21H15N5S
Molecular Weight
369.44
References & Citations
[1]Ullah S, et al. Urease inhibitory potential of pyridine-containing triazolothiadiazole and triazolothiadiazine scaffolds for the treatment of ulceration and kidney stone: in vitro screening, kinetics mechanism, and in silico computational analysis. J Biomol Struct Dyn. 2023 Dec 28:1-10.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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