MSA-2-Pt
MSA-2-Pt is an orally active STING agonist that has good cell membrane permeability. MSA-2-Pt can induce cell death by Pt, which may release damaged DNA to activate the cGAS-STING pathway. Besides, MSA-2-Pt can activate the STING pathway directly by MSA-2. MSA-2-Pt can be used for the research of cancer[1].
Product Specifications
UNSPSC
12352211
Target
STING
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/msa-2-pt.html
Solubility
10 mM in DMSO
Smiles
O=C(CCC(O[Pt]([NH3])(OC(CCC(C1=CC2=CC(OC)=C(OC)C=C2S1)=O)=O)[NH3])=O)C3=CC4=CC(OC)=C(OC)C=C4S3
Molecular Formula
C28H32N2O10PtS2
Molecular Weight
815.78
References & Citations
[1]Wang M, et al. Antitumor Effect of Platinum-Modified STING Agonist MSA-2[J]. ACS Omega, 2024.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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