Antibacterial agent 176
Antibacterial agent 176 (Compound 6f) is a potent PqsR antagonist. Antibacterial agent 176 has a good inhibitory effect on P. aeruginosa CF, and a significant inhibitory effect on the production of pyocyanin, 2-alkyl-4 (1H) -quinolones[1].
Product Specifications
CAS Number
9007-83-4
UNSPSC
12352005
Target
Bacterial
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/antibacterial-agent-176.html
Solubility
10 mM in DMSO
Smiles
OC(COC1=CC=C(C=C1)CC#N)CNC2=NC3=C(N2C(C)C)C=C(C=C3)Cl
Molecular Formula
C21H23ClN4O2
Molecular Weight
398.89
References & Citations
[1]Soukarieh F, et al. Design, Synthesis, and Evaluation of New 1H-Benzo[d]imidazole Based PqsR Inhibitors as Adjuvant Therapy for Pseudomonas aeruginosa Infections. J Med Chem. 2024 Jan 3.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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