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AT2 receptor ligand-1

AT2 receptor ligand-1 (compound 14) is a potent angiotensin AT2 receptor ligand with the Ki 4.9 nM. AT2 receptor ligand-1 shows high stability in microsomes of the sulfonamide ligands[1].

Product Specifications

UNSPSC

12352005

Target

Angiotensin Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein

Applications

Neuroscience-Neuromodulation

Field of Research

Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/at2-receptor-ligand-1.html

Solubility

10 mM in DMSO

Smiles

O=S(C1=C(C2=CC=CC(C(CN3C=CN=C3C(C)(C)C)=O)=C2)C=C(CC(C)C)S1)(NC4=NC=CC=N4)=O

Molecular Formula

C27H31N5O3S2

Molecular Weight

537.70

References & Citations

[1]Wannberg J, et al. N- (Heteroaryl) thiophene sulfonamides as angiotensin AT2 receptor ligands. Eur J Med Chem. 2024;265:116122.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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