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AT2 receptor ligand-1

Product Specifications

UNSPSC Description

AT2 receptor ligand-1(compound 14) is a potent angiotensin AT2 receptor ligand with the Ki 4.9 nM. AT2 receptor ligand-1 shows high stability in microsomes of the sulfonamide ligands[1].

Target Antigen

Angiotensin Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein

Applications

Neuroscience-Neuromodulation

Field of Research

Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/at2-receptor-ligand-1.html

Solubility

10 mM in DMSO

Smiles

O=S(C1=C(C2=CC=CC(C(CN3C=CN=C3C(C)(C)C)=O)=C2)C=C(CC(C)C)S1)(NC4=NC=CC=N4)=O

Molecular Weight

537.70

References & Citations

[1]Wannberg J, et al. N-(Heteroaryl)thiophene sulfonamides as angiotensin AT2 receptor ligands. Eur J Med Chem. 2024;265:116122.

Shipping Conditions

Room temperature

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-162125/AT2-receptor-ligand-1-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-162125/

Clinical Information

No Development Reported

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