AT2 receptor ligand-1
AT2 receptor ligand-1 (compound 14) is a potent angiotensin AT2 receptor ligand with the Ki 4.9 nM. AT2 receptor ligand-1 shows high stability in microsomes of the sulfonamide ligands[1].
Product Specifications
UNSPSC
12352005
Target
Angiotensin Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/at2-receptor-ligand-1.html
Solubility
10 mM in DMSO
Smiles
O=S(C1=C(C2=CC=CC(C(CN3C=CN=C3C(C)(C)C)=O)=C2)C=C(CC(C)C)S1)(NC4=NC=CC=N4)=O
Molecular Formula
C27H31N5O3S2
Molecular Weight
537.70
References & Citations
[1]Wannberg J, et al. N- (Heteroaryl) thiophene sulfonamides as angiotensin AT2 receptor ligands. Eur J Med Chem. 2024;265:116122.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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