FZQ-21
FZQ-21 (Compound 70P) is a soluble epoxide hydrolase (sEH) inhibitor, with an IC50 of 4 nM. FZQ-21 exhibits equal IC50 (1.5 nM) on inhibiting human sEH as EC5026 (1.7 nM). FZQ-21 can be used for research of sepsis[1].
Product Specifications
UNSPSC
12352005
Target
Epoxide Hydrolase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/fzq-21.html
Solubility
10 mM in DMSO
Smiles
O=C(NC1=CC=C(/C=C/C2=CC(NC(CC3=CC=CC=N3)=O)=CC=C2)C=C1)NCC4CCOCC4
Molecular Formula
C28H30N4O3
Molecular Weight
470.56
References & Citations
[1]Zi-Qiang Feng, et al. Discovery of a novel lead characterized by a stilbene-extended scaffold against sepsis as soluble epoxide hydrolase inhibitors. Eur J Med Chem. 2024 Jan 3:266:116113.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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