PRL-IN-1
Product Specifications
UNSPSC Description
PRL-IN-1 (compound 43) is a phosphatase of regenerating liver (PRL) inhibitor that directly binds the PRL1 trimer interface and obstructs PRL1 trimerization. PRL-IN-1 shows potent anticancer activities[1].
Target Antigen
Phosphatase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/prl-in-1.html
Solubility
10 mM in DMSO
Smiles
O=C(N/N=C\C1=CC=C(C(O)=O)C=C1)C2=CC=CC(N3CC(C=C(C)C(C)=C4)=C4C3)=C2
Molecular Weight
413.47
References & Citations
[1]Yunpeng Bai, et al. Novel Anticancer Agents Based on Targeting the Trimer Interface of the PRL Phosphatase. Cancer Res. 2016 Aug 15;76(16):4805-15.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-162119/PRL-IN-1-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-162119/
Clinical Information
No Development Reported
CAS Number
331431-75-5
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