PARP1-IN-18
PARP1-IN-18 (compound 25) is a potent PARP1 inhibitor with an IC50 value of 2.7 nM. PARP1-IN-18 has anticancer effects[1].
Product Specifications
CAS Number
2958609-64-6
UNSPSC
12352005
Target
PARP
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Epigenetics
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/parp1-in-18.html
Solubility
10 mM in DMSO
Smiles
O=C(NC1CC1)C2=CC=C(N3CCN(CC4=CC=C(C=C(C(F)F)C(N5)=O)C5=C4F)CC3)C(F)=N2
Molecular Formula
C24H23F4N5O2
Molecular Weight
489.47
References & Citations
[1]Sabnis RW. Novel Azaquinolones as PARP1 Inhibitors for Treating Cancer. ACS Med Chem Lett. 2021 Mar 16;12 (4) :524-525.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
PARP1
Frequently Asked Questions
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