Antitumor agent-128
Antitumor agent-128 (compound 1a) is an antitumor agent that elicits cell cycle arrest in both the G2/M and S phases, triggering apoptosis in A549 cells[1].
Product Specifications
CAS Number
1942910-49-7
UNSPSC
12352005
Target
Apoptosis
Type
Reference compound
Related Pathways
Apoptosis
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/antitumor-agent-128.html
Solubility
10 mM in DMSO
Smiles
O=C1N2C(C(C3=C2C=CC=C3)=O)=NC4=NC5=CC=CC=C5C=C41
Molecular Formula
C18H9N3O2
Molecular Weight
299.28
References & Citations
[1]Bao-Long Hou, et al. Natural products fragment-based design and synthesis of a novel pentacyclic ring system as potential MAPK inhibitor. Bioorg Med Chem Lett. 2023 Dec 31:99:129598.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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