BRCA2-RAD51-IN-1
Product Specifications
UNSPSC Description
BRCA2-RAD51-IN-1 (Compound 46) is a BRCA2-RAD51 inhibitor with an EC50 value of 28 μM. BRCA2-RAD51-IN-1 has antitumor activity[1].
Target Antigen
Others
Type
Reference compound
Related Pathways
Others
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/brca2-rad51-in-1.html
Solubility
10 mM in DMSO
Smiles
BrC1=CC=CC(C(NC2=CC(C(F)(F)F)=NN23)=CC3=O)=C1
Molecular Weight
358.11
References & Citations
[1]Myers SH, et al. An 19F NMR fragment-based approach for the discovery and development of BRCA2-RAD51 inhibitors to pursuit synthetic lethality in combination with PARP inhibition in pancreatic cancer. Eur J Med Chem. 2023 Dec 31;265:116114.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-162104/BRCA2-RAD51-IN-1-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-162104/
Clinical Information
No Development Reported
CAS Number
2830213-53-9
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