Keap1-Nrf2-IN-17
Keap1-Nrf2-IN-17 (compound 18) is a potent inhibitor of Keap1-Nrf2 protein-protein interaction[1].
Product Specifications
CAS Number
3042821-85-9
UNSPSC
12352005
Target
Keap1-Nrf2
Type
Reference compound
Related Pathways
NF-κB
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/keap1-nrf2-in-17.html
Solubility
10 mM in DMSO
Smiles
O=C(O)CN(S(=O)(C1=CC=C(C)C=C1)=O)C2=C3C(C=CC=C3)=C(N(S(=O)(C4=CC=C(C)C=C4)=O)CC(O)=O)C=C2OCC(O)=O
Molecular Formula
C30H28N2O11S2
Molecular Weight
656.68
References & Citations
[1]Sumi Lee, et al. Structural modification of C2-substituents on 1,4-bis (arylsulfonamido) benzene or naphthalene-N, N′-diacetic acid derivatives as potent inhibitors of the Keap1-Nrf2 protein-protein interaction. Eur J Med Chem. 2023 Dec 27:265:116104.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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