Topoisomerase I inhibitor 13
Selected Variant
HY-162091
Size: 1 Each
Topoisomerase I inhibitor 13 (Compound G11) is a Topo I inhibitor that inhibits cancer cell proliferation. Topoisomerase I inhibitor 13 significantly inhibits tumor growth in vivo[1].
Product Specifications
UNSPSC
12352005
Target
Topoisomerase
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/topoisomerase-i-inhibitor-13.html
Solubility
10 mM in DMSO
Smiles
O=C(/C=C/C1=CC=C(Cl)C([N+]([O-])=O)=C1)C2=NC=CC3=C2NC4=CC=CC=C43
Molecular Formula
C20H12ClN3O3
Molecular Weight
377.78
References & Citations
[1]Guo YL, et al. Design, synthesis, and biological evaluation of harmine derivatives as topoisomerase I inhibitors for cancer treatment. Eur J Med Chem. 2023 Dec 22;265:116061.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Price
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