FabH-IN-2

FabH-IN-2 (25), an antimicrobial agent, exhibits remarkable potential as an agent with an MIC range of 1.25-3.13 μg/mL against the tested bacterial strains and an IC50 of 2.0 μM against E. coli-derived FabH[1].

Product Specifications

CAS Number

3040281-87-3

UNSPSC

12352005

Target

Bacterial

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/fabh-in-2.html

Solubility

10 mM in DMSO

Smiles

O=C(NC1=CC(NC=C2C(OC)=O)=C2C=C1)C3=CC(OCCCO4)=C4C=C3

Molecular Formula

C20H18N2O5

Molecular Weight

366.37

References & Citations

[1]Haoyun Chang, et al. Target identification, and optimization of dioxygenated amide derivatives as potent antibacterial agents with FabH inhibitory activity. Eur J Med Chem. 2023 Dec 16:265:116064.