BTK-IN-32
BTK-IN-32 (compound C2) is a potent inhibitor of BTK. BTK-IN-32 activates full-length BTK and smaller multidomain BTK fragments instead of the isolated kinase domain[1].
Product Specifications
CAS Number
1015441-29-8
UNSPSC
12352005
Target
Btk
Type
Reference compound
Related Pathways
Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/btk-in-32.html
Solubility
10 mM in DMSO
Smiles
O=C(C1=CC(N(CC2=CC=CC(Cl)=C2)C(C3=CC=CC=C3S4=O)=O)=C4C=C1)NCCCN5CCN(CC6=CC=CC=C6)CC5
Molecular Formula
C35H35ClN4O3S
Molecular Weight
627.20
References & Citations
[1]Kueffer LE, et al. Screening and Characterization of Allosteric Small Molecules Targeting Bruton's Tyrosine Kinase. Biochemistry. 2024 Jan 2;63 (1) :94-106.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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