ZIKV-IN-8
ZIKV-IN-8 (Compound 9b) is a noncompetitive Zika virus (ZIKV) inhibitor. ZIKV-IN-8 shows the best anti-ZIKV activity with a selectivity index of 22.4. ZIKV-IN-8 has significant inhibition of ZIKV with an IC50 value of 25.6 μM. ZIKV-IN-8 can be used for the research of ZIKV infection[1].
Product Specifications
CAS Number
[3022924-04-2]
UNSPSC
12352005
Target
Influenza Virus
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/zikv-in-8.html
Solubility
10 mM in DMSO
Smiles
CC1=C(C(C2=O)=NN1C3=CC=C(OC)C=C3)C(C)=NN2CC4=CC([N+]([O-])=O)=CC=C4
Molecular Formula
C21H19N5O4
Molecular Weight
405.41
References & Citations
[1]Quang De Tran, et al. ZIKV Inhibitors Based on Pyrazolo[3,4-d]pyridazine-7-one Core: Rational Design, In Vitro Evaluation, and Theoretical Studies. ACS Omega 2023 8 (51), 48994-49008
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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