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ZIKV-IN-8

ZIKV-IN-8 (Compound 9b) is a noncompetitive Zika virus (ZIKV) inhibitor. ZIKV-IN-8 shows the best anti-ZIKV activity with a selectivity index of 22.4. ZIKV-IN-8 has significant inhibition of ZIKV with an IC50 value of 25.6 μM. ZIKV-IN-8 can be used for the research of ZIKV infection[1].

Product Specifications

CAS Number

[3022924-04-2]

UNSPSC

12352005

Target

Influenza Virus

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-anti-virus

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/zikv-in-8.html

Solubility

10 mM in DMSO

Smiles

CC1=C(C(C2=O)=NN1C3=CC=C(OC)C=C3)C(C)=NN2CC4=CC([N+]([O-])=O)=CC=C4

Molecular Formula

C21H19N5O4

Molecular Weight

405.41

References & Citations

[1]Quang De Tran, et al. ZIKV Inhibitors Based on Pyrazolo[3,4-d]pyridazine-7-one Core: Rational Design, In Vitro Evaluation, and Theoretical Studies. ACS Omega 2023 8 (51), 48994-49008

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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