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ChEs/MAOs-IN-1

ChEs/MAOs-IN-1 (Compound 4i) is a dual inhibitor of cholinesterases (ChEs) and monoamine oxidases (MAOs) .ChEs/MAOs-IN-1 has IC50 values of 0.048 μM, 0.89 μM, 3.58 μM, and 0.095 μM for AChE, BChE, MAO-B and MAO-B respectively. ChEs/MAOs-IN-1 can be used in the study of neurodegenerative diseases[1].

Product Specifications

UNSPSC

12352005

Target

Monoamine Oxidase

Type

Reference compound

Related Pathways

Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/ches-maos-in-1.html

Solubility

10 mM in DMSO

Smiles

O=C(N/N=C/C1=CC=CC(Cl)=C1Cl)C2=CC(OCO3)=C3C=C2

Molecular Formula

C15H10Cl2N2O3

Molecular Weight

337.16

References & Citations

[1]Kumar, V Pavan et al. Exploration of a library of piperonylic acid-derived hydrazones possessing variable aryl functionalities as potent dual cholinesterase and monoamine oxidase inhibitors. Molecular diversity vol. 27,6 (2023) : 2465-2489.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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