ChEs/MAOs-IN-1
ChEs/MAOs-IN-1 (Compound 4i) is a dual inhibitor of cholinesterases (ChEs) and monoamine oxidases (MAOs) .ChEs/MAOs-IN-1 has IC50 values of 0.048 μM, 0.89 μM, 3.58 μM, and 0.095 μM for AChE, BChE, MAO-B and MAO-B respectively. ChEs/MAOs-IN-1 can be used in the study of neurodegenerative diseases[1].
Product Specifications
UNSPSC
12352005
Target
Monoamine Oxidase
Type
Reference compound
Related Pathways
Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/ches-maos-in-1.html
Solubility
10 mM in DMSO
Smiles
O=C(N/N=C/C1=CC=CC(Cl)=C1Cl)C2=CC(OCO3)=C3C=C2
Molecular Formula
C15H10Cl2N2O3
Molecular Weight
337.16
References & Citations
[1]Kumar, V Pavan et al. Exploration of a library of piperonylic acid-derived hydrazones possessing variable aryl functionalities as potent dual cholinesterase and monoamine oxidase inhibitors. Molecular diversity vol. 27,6 (2023) : 2465-2489.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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