YPX-C-05
YPX-C-05 is a hydroxamic acid-based HDAC inhibitor. YPX-C-05 exerts significant vasodilatory effects. YPX-C-05 exhibits inhibitory effects on HDACs and increases histone H4 acetylation in endothelial cells. YPX-C-05 can be used for hypertension research[1].
Product Specifications
CAS Number
2894823-79-9
UNSPSC
12352005
Target
HDAC
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Epigenetics
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/ypx-c-05.html
Solubility
10 mM in DMSO
Smiles
COC1=CC(C2=CC=C(NC(NC3=CC=C(C(NO)=O)C=C3)=O)C=C2)=CC=C1
Molecular Formula
C21H19N3O4
Molecular Weight
377.39
References & Citations
[1]Pang PP, et al. The hydroxamic acid derivative YPX-C-05 alleviates hypertension and vascular dysfunction through the PI3K/Akt/eNOS pathway. Vascul Pharmacol. 2023 Dec 3;154:107251.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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