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YPX-C-05

YPX-C-05 is a hydroxamic acid-based HDAC inhibitor. YPX-C-05 exerts significant vasodilatory effects. YPX-C-05 exhibits inhibitory effects on HDACs and increases histone H4 acetylation in endothelial cells. YPX-C-05 can be used for hypertension research[1].

Product Specifications

CAS Number

2894823-79-9

UNSPSC

12352005

Target

HDAC

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage; Epigenetics

Applications

Neuroscience-Neuromodulation

Field of Research

Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/ypx-c-05.html

Solubility

10 mM in DMSO

Smiles

COC1=CC(C2=CC=C(NC(NC3=CC=C(C(NO)=O)C=C3)=O)C=C2)=CC=C1

Molecular Formula

C21H19N3O4

Molecular Weight

377.39

References & Citations

[1]Pang PP, et al. The hydroxamic acid derivative YPX-C-05 alleviates hypertension and vascular dysfunction through the PI3K/Akt/eNOS pathway. Vascul Pharmacol. 2023 Dec 3;154:107251.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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