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COX-1/2-IN-6

COX-1/2-IN-6 (compound 4 h) is a potent dual inhibitor of COX-1 and COX-2 with IC50s of 68 and 91 nM, respectively. COX-1/2-IN-6 can used in study inflammation diseases[1].

Product Specifications

CAS Number

327024-84-0

UNSPSC

12352005

Target

COX

Type

Reference compound

Related Pathways

Immunology/Inflammation

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/cox-1-2-in-6.html

Solubility

10 mM in DMSO

Smiles

O=C(C1=C(C)N(CC(O)=O)C(C2=CC=C(C3=CC=CC=C3)C=C2)=C1)OCC

Molecular Formula

C22H21NO4

Molecular Weight

363.41

References & Citations

[1]Naji S A, et al. Design and Evaluation of Synthesized Pyrrole Derivatives as Dual COX-1 and COX-2 Inhibitors Using FB-QSAR Approach[J]. ACS Omega, 2023.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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