COX-1/2-IN-6
COX-1/2-IN-6 (compound 4 h) is a potent dual inhibitor of COX-1 and COX-2 with IC50s of 68 and 91 nM, respectively. COX-1/2-IN-6 can used in study inflammation diseases[1].
Product Specifications
CAS Number
327024-84-0
UNSPSC
12352005
Target
COX
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/cox-1-2-in-6.html
Solubility
10 mM in DMSO
Smiles
O=C(C1=C(C)N(CC(O)=O)C(C2=CC=C(C3=CC=CC=C3)C=C2)=C1)OCC
Molecular Formula
C22H21NO4
Molecular Weight
363.41
References & Citations
[1]Naji S A, et al. Design and Evaluation of Synthesized Pyrrole Derivatives as Dual COX-1 and COX-2 Inhibitors Using FB-QSAR Approach[J]. ACS Omega, 2023.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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