RXP03
RXP03 is a MMPs inhibitor with the Ki of 20 nM, 2.5 nM, 10 nM, 5nM and 105 nM for MMP-2, MMP-8, MMP-9, MMP-11, MMP-14, respectively[1].
Product Specifications
CAS Number
284667-65-8
UNSPSC
12352005
Target
MMP
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/rxp03.html
Purity
98.82
Solubility
DMSO : 25 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
OP([C@H](CC1=CC=CC=C1)NC(OCC2=CC=CC=C2)=O)(C[C@@H](CCCC3=CC=CC=C3)C(N[C@@H](CC4=CNC5=C4C=CC=C5)C(N)=O)=O)=O
Molecular Formula
C39H43N4O6P
Molecular Weight
694.76
References & Citations
[1]Abdou MM, et al. Novel glycosyl prodrug of RXP03 as MMP-11 prodrug: design, synthesis and virtual screening. BMC Chem. 2023;17 (1) :167. Published 2023 Nov 25.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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