α-Amylase/α-Glucosidase-IN-7
Product Specifications
UNSPSC Description
α-Amylase/α-Glucosidase-IN-7 (Compound 3f) is a competitive α-glucosidase and α-amylase enzyme inhibitor with IC50 values of 18.52 and 20.25 µM, respectively. α-Amylase/α-Glucosidase-IN-7 can also effectively inhibit AChE and BChE, with IC50 values of 9.25 and 10.06 µM respectively. α-Amylase/α-Glucosidase-IN-7 can be used in diabetes and Alzheimer’s research[1].
Target Antigen
Amylases; Cholinesterase (ChE); Glycosidase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease;Neuronal Signaling
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/α-amylase-α-glucosidase-in-7.html
Solubility
10 mM in DMSO
Smiles
ClC1=CC=C(C2=NN=C(SCC3=CC=C(F)C=C3Cl)O2)C=C1
Molecular Weight
355.21
References & Citations
[1]Fatima B, et al. Multitargeted inhibition of key enzymes associated with diabetes and Alzheimer's disease by 1,3,4-oxadiazole derivatives: Synthesis, in vitro screening, and computational studies. Arch Pharm (Weinheim). 2023 Dec;356(12):e2300384.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-162036/α-Amylase-α-Glucosidase-IN-7-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-162036/
Clinical Information
No Development Reported
CAS Number
1038094-94-8
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