α-Amylase/α-Glucosidase-IN-7

α-Amylase/α-Glucosidase-IN-7 (Compound 3f) is a competitive α-glucosidase and α-amylase enzyme inhibitor with IC50 values of 18.52 and 20.25 µM, respectively. α-Amylase/α-Glucosidase-IN-7 can also effectively inhibit AChE and BChE, with IC50 values of 9.25 and 10.06 µM respectively. α-Amylase/α-Glucosidase-IN-7 can be used in diabetes and Alzheimer’s research[1].

Product Specifications

CAS Number

[1038094-94-8]

UNSPSC

12352005

Target

Amylases; Cholinesterase (ChE) ; Glycosidase

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease; Neuronal Signaling

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Metabolic Disease; Neurological Disease

Assay Protocol

https://www.medchemexpress.com/α-amylase-α-glucosidase-in-7.html

Solubility

10 mM in DMSO

Smiles

ClC1=CC=C(C2=NN=C(SCC3=CC=C(F)C=C3Cl)O2)C=C1

Molecular Formula

C15H9Cl2FN2OS

Molecular Weight

355.21

References & Citations

[1]Fatima B, et al. Multitargeted inhibition of key enzymes associated with diabetes and Alzheimer's disease by 1,3,4-oxadiazole derivatives: Synthesis, in vitro screening, and computational studies. Arch Pharm (Weinheim) . 2023 Dec;356 (12) :e2300384.