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FAK-IN-17

FAK-IN-17 is a focal adhesion kinase (FAK) inhibitor. FAK-IN-17 possesses anticancer activity against A549 and MDA-MB-231 cell lines with IC50 values of 130 nM and 94 nM[1].

Product Specifications

UNSPSC

12352005

Target

FAK

Type

Reference compound

Related Pathways

Protein Tyrosine Kinase/RTK

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/fak-in-17.html

Solubility

10 mM in DMSO

Smiles

ClC1=CN=C(NC2=CC=C(C(NC3CCOCC3)=O)C=C2)N=C1NC4=CC=CC=C4P(C)(C)=O

Molecular Formula

C24H27ClN5O3P

Molecular Weight

499.93

References & Citations

[1]Yixiang Sun, et al. Design, synthesis, and biological evaluation of diaminopyrimidine derivatives as novel focal adhesion kinase inhibitors. RSC Med Chem. 2023 Aug 21;14 (11) :2301-2314.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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