FAK-IN-17
FAK-IN-17 is a focal adhesion kinase (FAK) inhibitor. FAK-IN-17 possesses anticancer activity against A549 and MDA-MB-231 cell lines with IC50 values of 130 nM and 94 nM[1].
Product Specifications
UNSPSC
12352005
Target
FAK
Type
Reference compound
Related Pathways
Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/fak-in-17.html
Solubility
10 mM in DMSO
Smiles
ClC1=CN=C(NC2=CC=C(C(NC3CCOCC3)=O)C=C2)N=C1NC4=CC=CC=C4P(C)(C)=O
Molecular Formula
C24H27ClN5O3P
Molecular Weight
499.93
References & Citations
[1]Yixiang Sun, et al. Design, synthesis, and biological evaluation of diaminopyrimidine derivatives as novel focal adhesion kinase inhibitors. RSC Med Chem. 2023 Aug 21;14 (11) :2301-2314.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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