PB118
PB118 is a potent inhibitor of HDAC6 that plays an important role in the pathophysiology of Alzheimer's disease[1].
Product Specifications
UNSPSC
12352005
Target
HDAC
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Epigenetics
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/pb118.html
Solubility
10 mM in DMSO
Smiles
FC(C=C(C(NO)=O)C=C1)=C1CN2C3=CC=CC=C3CCCC2
Molecular Formula
C18H19FN2O2
Molecular Weight
314.35
References & Citations
[1]Prasenjit Mondal, et al. Structure-Based Discovery of A Small Molecule Inhibitor of Histone Deacetylase 6 (HDAC6) that Significantly Reduces Alzheimer's Disease Neuropathology. Adv Sci (Weinh) . 2023 Nov 21:e2304545.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
LV811409 1.0 µg DNA
TMEM146 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV-GFP-2A-Puro)
Sign In for Pricing
View Details 
MBS1395655-01 0.02 mg (E-Coli)
Recombinant Bradyrhizobium japonicum 3-isopropylmalate dehydratase large subunit 1 (leuC1)
Sign In for Pricing
View Details MBS1395655-02 0.02 mg (Yeast)
Recombinant Bradyrhizobium japonicum 3-isopropylmalate dehydratase large subunit 1 (leuC1)
Sign In for Pricing
View Details