Echothiopate iodide

Echothiopate iodide is a potent hBChE (human butyrylcholinesterase) inhibitor. Echothiopate iodide is a long-acting anticholinesterase agent. Echothiopate iodide can be used for glaucoma research[1][2].

Product Specifications

CAS Number

513-10-0

Product Name Alternative

Echothiophate iodide

UNSPSC

12352211

Hazard Statement

H300-H311+H331-H400

Target

Cholinesterase (ChE)

Type

Reference compound

Related Pathways

Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/echothiopate-iodide.html

Solubility

10 mM in DMSO

Smiles

O=P(SCC[N+](C)(C)C)(OCC)OCC.[I-]

Molecular Formula

C9H23INO3PS

Molecular Weight

383.23

Precautions

P261-P264-P270-P271-P273-P280-P302+P352-P304+P340-P330-P361+P364-P391-P403+P233-P405-P501

References & Citations

[1]Nachon F, et al. Role of water in aging of human butyrylcholinesterase inhibited by echothiophate: the crystal structure suggests two alternative mechanisms of aging. Biochemistry. 2005 Feb 1;44 (4) :1154-62.|[2]HUMPHREYS JA, et al. Systemic effects produced by echothiophate iodide in treatment of glaucoma. Arch Ophthalmol. 1963 Jun;69:737-43.