Crilvastatin
Crilvastatin (PMD 387) is a potent inhibitor of HMG-CoA reductase[1].
Product Specifications
CAS Number
120551-59-9
Product Name Alternative
PMD 387
UNSPSC
12352005
Target
HMG-CoA Reductase (HMGCR)
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/crilvastatin.html
Solubility
10 mM in DMSO
Smiles
O=C(OC1CC(C)(C)CC(C)C1)[C@H](CC2)NC2=O
Molecular Formula
C14H23NO3
Molecular Weight
253.34
References & Citations
[1]T Clerc, et al. Mechanisms of action in the liver of crilvastatin, a new hydroxymethylglutaryl-coenzyme A reductase inhibitor. Eur J Pharmacol. 1993 Apr 22;235 (1) :59-68.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 2
Available Sizes
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