HSD17B13-IN-7
HSD17B13-IN-7 (compound 1), a fluorophenol-containing compound, is a potent HSD17B13 inhibitor with IC50s of 0.18 μM and 0.25 μM β-estradiol and Leukotriene B4 as substrates, respectively. HSD17B13-IN-7 is a potent N-methyl-D-aspartate (NMDA) NR2B receptor antagonist. HSD17B13-IN-7 has the potential for non-alcoholic fatty liver disease research[1].
Product Specifications
CAS Number
863564-16-3
UNSPSC
12352005
Target
17β-HSD; iGluR
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel; Metabolic Enzyme/Protease; Neuronal Signaling
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/hsd17b13-in-7.html
Solubility
10 mM in DMSO
Smiles
FC1=C(O)C=CC(C(NC[C@]2(O)CC[C@H](COC3=CC=CC=C3)CC2)=O)=C1
Molecular Formula
C21H24FNO4
Molecular Weight
373.42
References & Citations
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
NMDA Receptor
Frequently Asked Questions
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