IMP-1575

IMP-1575 is the most potent Hedgehog acyltransferase (HHAT) inhibitor, with an IC50 of 0.75 μM for inhibition of purified HHAT. IMP-1575 can be used for the research of cancer[1].

Product Specifications

CAS Number

[3026255-85-3]

UNSPSC

12352005

Target

Hedgehog

Type

Reference compound

Related Pathways

Stem Cell/Wnt

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/imp-1575.html

Solubility

10 mM in DMSO

Smiles

O=C(N1CCC2=C([C@@H]1C3=NC(C)=CC=C3)C=CS2)CNCC(C)C

Molecular Formula

C19H25N3OS

Molecular Weight

343.49

References & Citations

[1]Ritzefeld M, et al.Design, Synthesis, and Evaluation of Inhibitors of Hedgehog Acyltransferase. J Med Chem. 1970,2:1061-1078.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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