IMP-1575
IMP-1575 is the most potent Hedgehog acyltransferase (HHAT) inhibitor, with an IC50 of 0.75 μM for inhibition of purified HHAT. IMP-1575 can be used for the research of cancer[1].
Product Specifications
CAS Number
[3026255-85-3]
UNSPSC
12352005
Target
Hedgehog
Type
Reference compound
Related Pathways
Stem Cell/Wnt
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/imp-1575.html
Solubility
10 mM in DMSO
Smiles
O=C(N1CCC2=C([C@@H]1C3=NC(C)=CC=C3)C=CS2)CNCC(C)C
Molecular Formula
C19H25N3OS
Molecular Weight
343.49
References & Citations
[1]Ritzefeld M, et al.Design, Synthesis, and Evaluation of Inhibitors of Hedgehog Acyltransferase. J Med Chem. 1970,2:1061-1078.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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