Carbonic anhydrase inhibitor 17
Carbonic anhydrase inhibitor 17 (compound 7c), pyridazine-tethered sulfonamide, is a carbonic anhydrase II inhibitor with IC50 of 0.63 nM[1].
Product Specifications
CAS Number
3033849-05-4
UNSPSC
12352005
Target
Carbonic Anhydrase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/carbonic-anhydrase-inhibitor-17.html
Solubility
10 mM in DMSO
Smiles
O=C(NC1=CC=C(C=C1)S(=O)(N)=O)CSC2=NN=C(C=C2)C3=CC=C(C=C3)Cl
Molecular Formula
C18H15ClN4O3S2
Molecular Weight
434.92
References & Citations
[1]Tawfik HO, et al. Discovery of Novel Pyridazine-Tethered Sulfonamides as Carbonic Anhydrase II Inhibitors for the Management of Glaucoma. J Med Chem. 2024 Jan 25;67 (2) :1611-1623.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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