Microtubule inhibitor 9
Microtubule inhibitor 9 (Compound O-7) is a 2-Aryl-1H-benzo [d] imidazole derivative with in vitro anticancer activity. Microtubule inhibitor 9 can induce cell cycle arrest at the G2/M phase and early apoptosis. Microtubule inhibitor 9 inhibits cancer cell migration by inhibiting wound healing and colony formation[1].
Product Specifications
UNSPSC
12352005
Target
Apoptosis
Type
Reference compound
Related Pathways
Apoptosis
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/microtubule-inhibitor-9.html
Solubility
10 mM in DMSO
Smiles
C1(C2=CC=CC3=C2C=CC=C3)=NC4=CC(OC5=CC=CC=C5)=CC=C4N1
Molecular Formula
C23H16N2O
Molecular Weight
336.39
References & Citations
[1]Park S J, et al. The microtubule cytoskeleton: A validated target for the development of 2-Aryl-1H-benzo [d] imidazole derivatives as potential anticancer agents[J]. Biomedicine & Pharmacotherapy, 2024, 171: 116106.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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