Carbonic anhydrase/AChE-IN-2
Product Specifications
UNSPSC Description
Carbonic anhydrase/AChE-IN-2 (compound 19) is a selective acetylcholinesterase (AChE) and carbonic anhydrase (CA) inhibitor, with Ei of 5.07 nM, 24.42 nM and 19.95 nM for AChE, hCAI and hCAII, respectively[1].
Target Antigen
Carbonic Anhydrase; Cholinesterase (ChE)
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease;Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/carbonic-anhydrase-ache-in-2.html
Solubility
10 mM in DMSO
Smiles
O=C(/C=C/C1=CC=C(C(F)(F)F)C=C1)C2=CC=C(OC)C(Br)=C2
Molecular Weight
385.18
References & Citations
[1]Aydin BO, et al. Organohalogen chalcones: design, synthesis, ADMET prediction, molecular dynamics study and inhibition effect on acetylcholinesterase and carbonic anhydrase. Mol Divers. 2024 Jan 3.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-161143/Carbonic-anhydrase-AChE-IN-2-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-161143/
Clinical Information
No Development Reported
Curated Selection
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