Carbonic anhydrase/AChE-IN-2

Carbonic anhydrase/AChE-IN-2 (compound 19) is a selective acetylcholinesterase (AChE) and carbonic anhydrase (CA) inhibitor, with Ei of 5.07 nM, 24.42 nM and 19.95 nM for AChE, hCAI and hCAII, respectively[1].

Product Specifications

UNSPSC

12352005

Target

Carbonic Anhydrase; Cholinesterase (ChE)

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/carbonic-anhydrase-ache-in-2.html

Solubility

10 mM in DMSO

Smiles

O=C(/C=C/C1=CC=C(C(F)(F)F)C=C1)C2=CC=C(OC)C(Br)=C2

Molecular Formula

C17H12BrF3O2

Molecular Weight

385.18

References & Citations

[1]Aydin BO, et al. Organohalogen chalcones: design, synthesis, ADMET prediction, molecular dynamics study and inhibition effect on acetylcholinesterase and carbonic anhydrase. Mol Divers. 2024 Jan 3.