MDOLL-0229
MDOLL-0229 (compound 27) is an antiviral agent that targets SARS-CoV-2 Mac1 and repress coronavirus replication. MDOLL-0229 inhibits SARS-CoV-2 Mac1 with an IC50 of 2.1 µM[1].
Product Specifications
CAS Number
3036752-42-5
UNSPSC
12352005
Target
SARS-CoV
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/mdoll-0229.html
Solubility
10 mM in DMSO
Smiles
O=C(OC)C1=C(NC([C@]2([H])CCCC[C@@]2([H])C(O)=O)=O)SC3=C1CCCCCC3
Molecular Formula
C20H27NO5S
Molecular Weight
393.50
References & Citations
[1]Sarah Wazir, et al. Discovery of 2-amide-3-methylester thiophenes that target SARS-CoV-2 Mac1 and repress coronavirus replication, validating Mac1 as an anti-viral target. bioRxiv. December 27, 2023.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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