Z8554052021
Z8554052021 (compound 2021) is a potent CaSR and indeed GPCR positive allosteric modulator (PAM) with an EC50 of 3.3 nM. Z8554052021 has the potential for hyperparathyroidism research[1].
Product Specifications
UNSPSC
12352005
Target
CaSR
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/z8554052021.html
Solubility
10 mM in DMSO
Smiles
C[C@H](N[C@@H](C)C1=CC(N2N=CC=C2)=CC=C1)C3=CSC4=C3C=CC=C4
Molecular Formula
C21H21N3S
Molecular Weight
347.48
References & Citations
[1]Fangyu Liu, et al. Structure-based discovery of positive allosteric modulators for the calcium sensing receptor. bioRxiv, December 27, 2023.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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