OX04529
Product Specifications
UNSPSC Description
OX04529 (compound 69) is a potent, selective and orally active agonist of GPR84. OX04529 inhibits FSK-induced cAMP production with an EC50 of 0.0185 nM. OX04529 displayed excellent potency, high G-protein signaling bias[1].
Target Antigen
GPR84
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/ox04529.html
Solubility
10 mM in DMSO
Smiles
[O-][N+]1=CC(CCCC2=CC=C(C(C(F)(F)F)=C2)Cl)=CC(O)=C1
Molecular Weight
331.72
References & Citations
[1]Wang P, et al. Development of Highly Potent, G-Protein Pathway Biased, Selective, and Orally Bioavailable GPR84 Agonists. J Med Chem. 2024 Jan 11;67(1):110-137.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-161107/OX04529-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-161107/
Clinical Information
No Development Reported
Curated Selection
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