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β-catenin/BCL9 PPI-IN-1

β-catenin/BCL9 PPI-IN-1 (compound B4) is a potent inhibitor of β catenin/B-Cell lymphoma 9 protein protein interaction (β catenin/BCL9 PPI) with the IC50 value of 2.25 μM[1].

Product Specifications

UNSPSC

12352005

Target

β-catenin

Type

Reference compound

Related Pathways

Stem Cell/Wnt

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/β-catenin-bcl9-ppi-in-1.html

Solubility

10 mM in DMSO

Smiles

OC1=CC(O)=C(C(C(O)=C(C2=CC(O)=C(O)C=C2)O3)=O)C3=C1C4=CC=C(C)C=C4

Molecular Formula

C22H16O7

Molecular Weight

392.36

References & Citations

[1]Xinyan Peng, et al. Design, synthesis, and biological evaluation of novel 8-substituted quercetin derivatives targeting the β‑catenin/B-cell lymphoma 9 interaction. Bioorg Med Chem Lett. 2023 Dec 13:98:129591.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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