β-catenin/BCL9 PPI-IN-1
β-catenin/BCL9 PPI-IN-1 (compound B4) is a potent inhibitor of β catenin/B-Cell lymphoma 9 protein protein interaction (β catenin/BCL9 PPI) with the IC50 value of 2.25 μM[1].
Product Specifications
UNSPSC
12352005
Target
β-catenin
Type
Reference compound
Related Pathways
Stem Cell/Wnt
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/β-catenin-bcl9-ppi-in-1.html
Solubility
10 mM in DMSO
Smiles
OC1=CC(O)=C(C(C(O)=C(C2=CC(O)=C(O)C=C2)O3)=O)C3=C1C4=CC=C(C)C=C4
Molecular Formula
C22H16O7
Molecular Weight
392.36
References & Citations
[1]Xinyan Peng, et al. Design, synthesis, and biological evaluation of novel 8-substituted quercetin derivatives targeting the β‑catenin/B-cell lymphoma 9 interaction. Bioorg Med Chem Lett. 2023 Dec 13:98:129591.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-161087/β-catenin-BCL9-PPI-IN-1-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-161087/
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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